The forward scored on what was also his 217th league appearance for City, who he joined from Atletico Madrid in 2011.
High praise for the Southampton midfielder, who has scored a few quality goals from set-pieces in his time at Southampton.
Aguero has achieved a number of goalscoring highs for City in the a year ago, becoming the club's all-time top goalscorer against Napoli in November 2017.
Sterling, 23, has now been directly involved in 39 Premier League goals since the start of last season, only Mohamed Salah (50) has been involved in more.
Chelsea reacted by bringing on dangerman Eden Hazard and Mateo Kovacic, and within minutes, were back in front.
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More than 70 rescue boats came to the scene, including three floating cranes with a total capacity of 125 tonnes. He refused, and she went on to hit his head with her mobile phone before they exchanged blows.
Raheem Sterling hopes to give Manchester City fans plenty more reason to chant his name after starring in Sunday's demolition of Southampton. "We were not stable behind", he said.
City were rampant from the off and took the lead after just six minutes when Wesley Hoedt's attempted clearance of a Leroy Sane cross ended up in the back of his own net.
And it will now be seven Premier League games without a win following their visit to the Etihad.
Shane Long should have pulled one back for the south coast side late on, only to shoot wide from eight yards, and it was then left to Sane to stroke the ball out of McCarthy's reach from the edge of the area to cap another impressive City display.
"It was an incredible performance but still with the young guys like him and Leroy [Sane] I would feel he can improve".
Southampton improved at the start of the second half, with James Ward-Prowse and Ings - via wicked deflection off Fernandinho - forcing Ederson to make fine stops.
Sterling did in the 67th minute when he latched onto Aguero's perfectly-weighted pass to score his second goal of the afternoon.