Asked about Luis Enrique at his news conference on Thursday, Wenger said: "I have a high opinion of him".
The closest Wenger ever came to a European trophy was losing the 2006 Champions League final to Barcelona, which he admitted was his "biggest regret" from his two-decade spell at the club.
Sanchez's career at United might have got off to a slow start, but his performances have improved and his goal against Spurs on Saturday was a timely reminder of what Arsenal have lost.
Much is likely to depend on Diego Costa.
Diego Costa is set to feature for the Spainish side, having recovered from a hamstring injury.
It's bad news for Arsenal.
A top-four Premier League finish is nearly certainly beyond Wenger's side, but since losing at Brighton they have scored three goals or more in six of those nine matches, all at the Emirates Stadium.
The Brazilian-born Spain striker also somehow dodged a red in the 2015 clash when Gabriel was sent off despite clashing with Laurent Koscielny.
Trump willing to help sift through Cohen raid evidence: lawyer
Trump was also asked about Cohen's decision to plead the Fifth Amendment in a case brought by Daniels over the hush agreement. Michael Avenatti tweeted "This is a stunning development".
Wenger has been in charge at Arsenal for more than two decades.
The report claims that he has discussed a contract with Chelsea and that Arsenal are a less appealing prospect for him.
Wenger has said he will stay out of the search for his successor, but he agreed with chief executive Ivan Gazidis that the club must not be afraid to make a "bold" hire - and was open to the idea of hiring a former player to take over. It's a template to follow this time around.
The Red Devils will look to rip those scars wide open on Sunday and with seven wins in their last 10 home league meetings against Wenger's side, they'll be confident of claiming victory. Bayern Munich and Barcelona have ruthlessly punished their gung-ho approach on several occasions in the recent past, and the lack of game management was even more apparent against Monaco in 2015.
But Wenger has played down quite how fit Cech really is and feels that Ospina - who is the club's cup keeper, turning out eight times in Europe this season - deserves his chance.
In terms of the head-to-head stats, Arsenal have never faced Atletico in a competitive match in Europe but defeated them 2-1 in the Emirates Cup pre-season friendly which took place in 2009.
"They've done fantastically well, so I'm sure that one day when the time is right, he'll be a fantastic manager".