Prince Charles officially opened the Games with help from World Champion hurdler and Gold Coast local, Sally Pearson, handing over the Queen's Baton.
Titmuss had been tipped to become the first woman to win the 200-400-800 freestyle treble at the same Commonwealth Games since fellow Australian Karen Moras did it in 1970.
Australia, with sisters Bronte and Cate Campbell, Emma McKeon and Shayna Jack, clocked a time of 3 minutes, 30.5 seconds Thursday night at the Gold Coast Aquatic Centre. Kelland O'Brien joined Leigh Howard, Alex Porter and Sam Welsford to beat England for the title and lower the previous record of 3:50.265 which Britain set at Rio de Janeiro in 2016.
Canada finished second in 3:33.92 with England third nearly five seconds further back.
While Australia came away with two gold, three silver and four bronze from the pool, they were upstaged by an England team who took home four gold medals of their own. "My coach said 'the atmosphere out there is electric, go out, soak it up.' I think that is what we have done".
"I think that was really incredible". Horton recorded a time of 3:43.76, with McLoughlin following in 3:45.21.
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"I probably feel more emotion here than in Rio because the whole crowd is cheering for you", Horton said.
"That didn't happen so much in Rio".
Muhammad Azroy Hazalwa won the first of two gold medals for Malaysia in weightlifting, a result he celebrated by dancing and doing a lap of honour of the lifting area.India also won their first gold through women's 48kg world champion weightlifter Chanu Saikham Mirabai, who set three new Commonwealth records in her runaway win. "Ten thousand people cheering for you is pretty unreal".
The rain didn't dampen the spirits of 35,000 spectators at the Commonwealth Games Opening Ceremony last night.
Wilmott, beaten by Miley in the 2014 Glasgow final, fought back tenaciously in the final freestyle leg to pip the Scot by 0.26secs with Australia's Blair Evans third.
"I've raced against Hannah in every meet and I've been second every time", Willmott told reporters. Australian Matt Willis took the bronze.