Ant was absent from last night's show as Declan Donnelly hosted solo for the first time.
It's after the other half of the duo - Ant McPartlin's return to rehab following his drink-driving charge.
Dr. Helen Driscoll is a psychologist at Sunderland University and feels for December.
According to the Mirror Online, Ant won't be far from Dec's mind as he opens the show.
The presenter is without his normal sidekick after Ant stepped down from his TV commitments when he was charged with drink driving earlier this month.
And he waited until the very end of the show to express his heartfelt thanks for the support the audience had given him. "We have got a jam-packed show, this week we have lots to cram in and twice the amount of work to do", he joked. He appeared in the opening titles and also in the continuation of pre-recorded sketch Saturday Knight Takeaway which also starred Joanna Lumley in her regular role.
ITVSaturday Night Takeaway Dec introduced Davina to the show
Merchant then asked Dec if he needed a hand presenting as there was "a little bit of space on the stage", before the pair exchanged a joke about their height difference.
"Its weird to see only Dec's name but anyways All the best Dear Dec. Ant we will miss you.Get well soon Dear".
Social media was flooded with messages of support and congratulations.
"I know Ant would be proud of you".
Viewers at home dubbed their appearance together as the "Davina and Dec" show as there were mixed reviews for the new double act.
Donnelly who recently confirmed he is going to be a father, will also present next week's final episode in Florida alone.
There's been much speculation over the past few days as to whether Dec will address Ant when he hosts the show alone, as it was reported that "show chiefs have been agonising over whether Dec should apologise for Ant's no-show, ignore the incident or have no mention of Ant at all".
Pope presides over Good Friday amid increased security
Those marching said they want to call attention to the many social evils that still plague communities, all over the world. Another passer-by, Eric, who was also happy to see the re-enactment, said: "Is come I come up and buck up inna this".